Cancer survival statistics for patients and healthcare professionals – a tutorial of real-world data analysis

Monitoring the survival of cancer patients by using data collected by population-based cancer registries is an important component of cancer control. In this arrangement, the survival of patients often summarized using the survival clean, the survival of cancer if there is no other possible causes of death.

Although hygiene is the gold standard to compare survival between groups or from time to time, it is less relevant to understanding the real world patient prognosis anticipated. In this review, we will explain the statistical concepts targeted towards patients, physicians and health care professionals that the survival of cancer patients summarizes the assumption that there are other causes of death.

In particular, we explain the proper use, interpretation and assumptions behind the statistical methods for competing risks, loss of life expectancy for cancer and conditional survival. These concepts are relevant when producing statistics on risk communication between doctor and patient, the planning for the use of health resources, or other applications when consideration both cancerous and competing risk of death is required.

To reinforce the concepts, we used population-based data Swedish patients diagnosed with breast cancer, prostate, colon and chronic myeloid leukemia. We conclude that when choosing between steps Summary of survival are very important to characterize research purposes and to determine the nature of the hypothesis under investigation. Terminology and style of reporting options should be carefully tailored to the target audience and can range from a summary for readers of scientific publications specialist for interactive online tools intended for the layman.

Assessment of the Regulatory Dialogue Between Pharmaceutical Companies and the European Medicines Agency on the Choice of Noninferiority Margins
Assessment of the Regulatory Dialogue Between Pharmaceutical Companies and the European Medicines Agency on the Choice of Noninferiority MarginsAssessment of the Regulatory Dialogue Between Pharmaceutical Companies and the European Medicines Agency on the Choice of Noninferiority Margins

TRP channel agonist orally declare stimulates the secretion of saliva and modify the saliva proteome

natural compounds that can stimulate the secretion of saliva interest in developing treatments for xerostomia, dry mouth perception, which affects between 10 and 30% of the adult and elderly population. Chemesthetic transient receptor potential (TRP) channel expressed in the mucosal surface of the mouth. TRPV1 agonist capsaicin and piperine have been shown to increase the flow of saliva when introduced into the oral cavity but the nature of the agonist sialogogic other TRP channels have not been investigated.

In this study we have determined a different effect on the flow of TRP channel agonists and protein composition of saliva. Rinse mouth with TRPV1 agonist nonivamide or menthol, a TRPM8 agonist, increased saliva around the mouth (WMS) flows and total protein secretion compared with unstimulated saliva, rinse the vehicle control or cinnamaldehyde, TRPA1 agonist.

Nonivamide also improve the flow of labial minor salivary glands but parotid saliva flow rate is not increased. TRP channel agonists influence on the composition and function of the salivary proteome multi-batch investigated using quantitative mass spectrometry method new to saliva proteomics.

MM-102

B2364-25
EUR 588

MM-102

B2364-5
EUR 185

PPQ-102

B3504-10 10 mg
EUR 242

PPQ-102

B3504-5 5 mg
EUR 151

PPQ-102

B3504-50 50 mg
EUR 863

PM 102

B5517-1 1 mg
EUR 601

MM-102

HY-12220 10mg
EUR 298

IAXO-102

HY-125171 50mg
EUR 1944

PPQ-102

HY-14179 100mg
EUR 1221

BGB-102

HY-15732 10mg
EUR 6041

EL-102

HY-16187 10mM/1mL
EUR 376

LSZ-102

HY-111486 50mg
EUR 3321

p38 Antibody

35478-100ul 100ul
EUR 390

p38 Antibody

48644-100ul 100ul
EUR 333

p38 Antibody

48644-50ul 50ul
EUR 239

p38 antibody

70R-51505 100 ul
EUR 268
Description: Purified Polyclonal p38 antibody

p38 antibody

70R-51506 100 ul
EUR 287
Description: Purified Polyclonal p38 antibody

p38 Antibody

20-abx007541
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
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  • 30 ul
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p38 Antibody

20-abx133223
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  • EUR 439.00
  • EUR 189.00
  • 100 ul
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p38 Antibody

20-abx141038
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  • EUR 537.00
  • EUR 217.00
  • 100 ul
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  • Shipped within 5-10 working days.

p38 protein

E20-80078 20ug
EUR 408

p38 protein

E20-80079 20ug
EUR 408

p38 Antibody

abx236076-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

anti-p38

YF-PA11120 50 ug
EUR 363
Description: Mouse polyclonal to p38

anti-p38

YF-PA11121 100 ug
EUR 403
Description: Rabbit polyclonal to p38

anti-p38

YF-PA23519 50 ul
EUR 334
Description: Mouse polyclonal to p38

anti-p38

YF-PA23520 50 ul
EUR 334
Description: Mouse polyclonal to p38

anti-p38

YF-PA23521 50 ul
EUR 334
Description: Mouse polyclonal to p38

LB (Lennox)

102 500 g
EUR 101

BP-1-102

HY-100493 100mg
EUR 1345

MM-102 (TFA)

HY-12220A 10mM/1mL
EUR 263

SB-203580 p38 MAPK(p38 MAP kinase) Inhibitor

E1B1863 1mg
EUR 161

P38 delta protein

30R-2868 5 ug
EUR 503
Description: Purified recombinant Human P38 delta protein

p38 alpha protein

30R-2870 5 ug
EUR 503
Description: Purified recombinant Human p38 alpha protein

p38 beta protein

30R-2875 5 ug
EUR 503
Description: Purified recombinant Human p38 beta protein

p38 MAPK antibody

20R-1572 100 ug
EUR 705
Description: Rabbit polyclonal p38 MAPK antibody

P38 MAPK antibody

20R-2087 50 ug
EUR 281
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody

20R-2088 50 ug
EUR 281
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody

20R-2403 50 ug
EUR 281
Description: Rabbit polyclonal P38 MAPK antibody

p38 MAPK antibody

20R-2950 100 ul
EUR 393
Description: Rabbit polyclonal p38 MAPK antibody

p38 MAPK antibody

10R-8422 100 ul
EUR 393
Description: Mouse monoclonal p38 MAPK antibody

p38 MAPK Antibody

49379-100ul 100ul
EUR 333

p38 MAPK Antibody

49379-50ul 50ul
EUR 239

p38 Polyclonal Antibody

41305-100ul 100ul
EUR 252

p38 Polyclonal Antibody

41305-50ul 50ul
EUR 187

p38 Polyclonal Antibody

41306-100ul 100ul
EUR 252

p38 Polyclonal Antibody

41306-50ul 50ul
EUR 187

Anti-p38 alpha

DB-1039 100 tests
EUR 474

Anti-p38 beta

DB-1040 100 tests
EUR 474

Anti-p38 gamma

DB-1041 100 tests
EUR 474

Anti-p38 delta

DB-1042 100 tests
EUR 474

Anti-p38-a

DB-161-0.05 50 μl
EUR 269

Anti-p38-a

DB-161-0.1 100 μl
EUR 422

Anti-p38-b

DB-162-0.05 50 μl
EUR 269

Anti-p38-b

DB-162-0.1 100 μl
EUR 422

Anti-p38-g

DB-163-0.05 50 μl
EUR 269

Anti-p38-g

DB-163-0.1 100 μl
EUR 422

Anti-p38-d

DB-164-0.05 50 μl
EUR 269

Anti-p38-d

DB-164-0.1 100 μl
EUR 422

Anti-p38 alpha

DB1039 100 tests
EUR 474

Anti-p38 beta

DB1040 100 tests
EUR 474

Anti-p38 gamma

DB1041 100 tests
EUR 474

Anti-p38 delta

DB1042 100 tests
EUR 474

p38 beta, Active

7763-100
EUR 4345

p38 beta, Active

7763-5
EUR 370

Anti-p38 Antibody

A00176 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for p38 Antibody (MAPK14) detection.tested for WB in Human, Mouse, Rat.

p38 MAPK antibody

70R-33398 100 ug
EUR 327
Description: Rabbit polyclonal p38 MAPK antibody

p38 MAPK antibody

70R-33400 100 ug
EUR 327
Description: Rabbit polyclonal p38 MAPK antibody

P38 MAPK antibody

70R-34325 100 ug
EUR 327
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody

70R-34327 100 ug
EUR 327
Description: Rabbit polyclonal P38 MAPK antibody

p38 (pT180) Antibody

20-abx009863
  • EUR 314.00
  • EUR 467.00
  • EUR 203.00
  • 100 ul
  • 200 ul
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p38 (pY323) Antibody

20-abx133058
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  • EUR 467.00
  • EUR 203.00
  • 100 ul
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  • 30 ul
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p38 (pY182) Antibody

20-abx134951
  • EUR 384.00
  • EUR 606.00
  • EUR 230.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

p38 Blocking Peptide

20-abx161932
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg
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p38 MAPK Antibody

20-abx012798
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

p38 MAPK Antibody

20-abx012875
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

p38 Blocking Peptide

20-abx061736
  • EUR 258.00
  • EUR 384.00
  • 1 mg
  • 5 mg
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p38 Blocking Peptide

20-abx062080
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg
  • Shipped within 5-10 working days.

p38 MAPK Antibody

AF6455 200ul
EUR 304
Description: p38 MAPK Antibody detects endogenous levels of total p38 MAPK.

p38 MAPK Antibody

AF6456 200ul
EUR 304
Description: p38 MAPK Antibody detects endogenous levels of total p38 MAPK.

p38 MAPK Antibody

AF6457 200ul
EUR 304
Description: p38 MAPK Antibody detects endogenous levels of total p38 MAPK.

p38 MAPK Antibody

abx236077-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

p38 Polyclonal Antibody

ABP53838-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human p38 around the non-phosphorylation site of T180
  • Applications tips:
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody

ABP53838-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human p38 around the non-phosphorylation site of T180
  • Applications tips:
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody

ABP53838-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human p38 around the non-phosphorylation site of T180
  • Applications tips:
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody

ABP53839-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human p38 around the non-phosphorylation site of Y182
  • Applications tips:
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody

ABP53839-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human p38 around the non-phosphorylation site of Y182
  • Applications tips:
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody

ABP53839-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human p38 around the non-phosphorylation site of Y182
  • Applications tips:
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 MAPK Antibody

ABF6456 100 ug
EUR 438

p38 Polyclonal Antibody

ABP52112-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182
  • Applications tips:
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody

ABP52112-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182
  • Applications tips:
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody

ABP52112-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182
  • Applications tips:
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody

ABP52113-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human p38 around the non-phosphorylation site of Y323
  • Applications tips:
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody

ABP52113-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human p38 around the non-phosphorylation site of Y323
  • Applications tips:
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody

ABP52113-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human p38 around the non-phosphorylation site of Y323
  • Applications tips:
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody

ABP57354-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human p38
  • Applications tips:
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

Inter-personal and inter-rinse variation observed in the secreted proteomes and, using a new bioinformatics methods, inter-day variation is identified with some mouth rinses. Significant changes in the specific salivary proteins were identified after all mouth rinses. In the case of nonivamide, this change was associated with a functional shift in the WMS issued, especially representation over non-cystatins saliva and saliva were confirmed by immunoassay. This study provides new evidence of the impact of TRP channel agonist in the salivary proteome and the salivary secretion stimulation by channel TRPM8 agonist, which demonstrated that TRP channel agonists are potential candidates to develop a treatment for patients with xerostomia.